The Global Hepatic Encephalopathy Market size is anticipated to grow at a CAGR of 5.4% over the forecast period. Hepatic encephalopathy (HE) is a disorder usually detected in patients suffering from cirrhosis. In all those with acute liver failure and those with cirrhosis associated with end stage liver disease, HE is a symptom of poor prognosis, and it is associated with considerably high mortality. Liver cirrhosis is a gastroenterological disease characterized by gradual, progressive, and permanent fibrous tissue (scar) replacement of liver cells that prevents proper functioning of the liver.
Generally, liver cirrhosis affects up to 1 percent of the U.S. and EU population, according to the National Center for Biotechnology Information (NCBI): 2014. Due to HE related complications, between 180,000 and 290,000 patients with cirrhosis in the US are hospitalized every year. Once hepatic encephalopathy develops, after five years, mortality reaches 22-35%.
Increased hospitalization and care bills are also correlated with HE. In addition, in about 70 percent of cirrhosis cases, slight symptoms of HE are found. For the prevention of hepatic encephalopathy, multiple forms of experimental medications are in the pipeline. The growth of the global hepatic encephalopathy market is being driven by the rising cases of HE. Further, the market growth is also expected to be powered by a growing number of products in the pipeline for HE care.
Hepatic Encephalopathy Market, By Drug
Based on drugs, the hepatic encephalopathy market is categorized into antibiotic, laxatives, and others. In order to delay the growth of bacteria in the intestine, including bacteria that contain ammonia, antibiotics such as Rifaximin and Metronidazole can be used. This is expected to support the growth of the antibiotic segment over the next few years.
Hepatic Encephalopathy Market, By Type
Based on type, the global market has been segmented into type A, type B, and type C. Type C is the most common hepatic encephalopathy seen in patients with cirrhosis or advanced fibrosis. Hepatic encephalopathy type C is mainly associated with cirrhosis. When destructive fibrosis matures, cirrhosis is the last step of progressive liver disease. Increasing prevalence of cirrhosis is expected to drive the growth of the type C segment.
Hepatic Encephalopathy Market, By Distribution Channel
Based on the distribution channel, the hepatic encephalopathy market is categorized into hospitals, retail, and online channels. The hospital segment is going to dominate the market during the forecast period. Increasing investment in healthcare and drug development, increasing prevalence of diseases, and growing patient pool are the main factors that are expected to propel the growth of the hospital segment over other segments.
Hepatic Encephalopathy Market, By Treatment
Based on treatments, the hepatic encephalopathy market is categorized into lactulose, antibiotics, probiotics, branched-chain amino acids, and liver transplantation. Lactulose is a synthetic form of sugar that is not absorbed into the body. Lactulose is also used in people with liver disease to decrease the level of ammonia in their blood. By extracting ammonia from the blood into the colon, from where ammonia is eliminated from the body. The increasing usage of lactulose for the treatment of HE will augment the growth of this segment.
Hepatic Encephalopathy Market, By Regions
In the worldwide hepatic encephalopathy industry, North America is holding a leading position. The domination of the region is due to the growing consumer awareness about multiple care choices and increasing demand for treatment. Due to increasing population and rising demand for fast diagnosis globally, the market for hepatic encephalopathy is expected to grow in this region.
Key Developments in the Hepatic Encephalopathy Market
Some Key Findings of the Hepatic Encephalopathy Market Report Include:
By Distribution Channel
Detailed scope covering all the major segments in the market
In line data validations to ensure data precision
Market recommendations supporting decision making processes
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